An Immune Clonal Selection Algorithm for Synthetic Signature Generation

The collection of signature data for system development and evaluation generally requires significant time and effort. To overcome this problem, this paper proposes a detector generation based clonal selection algorithm for synthetic signature set generation. The goal of synthetic signature generation is to improve the performance of signature verification by providing more training samples. Our method uses the clonal selection algorithm to maintain the diversity of the overall set and avoid sparse feature distribution. The algorithm firstly generates detectors with a segmented r-continuous bits matching rule and P-receptor editing strategy to provide a more wider search space. Then the clonal selection algorithm is used to expand and optimize the overall signature set. We demonstrate the effectiveness of our clonal selection algorithm, and the experiments show that adding the synthetic training samples can improve the performance of signature verification

Towards Stable Co-saliency Detection and Object Co-segmentation

In this paper, we present a novel model for simultaneous stable co-saliency detection (CoSOD) and object co-segmentation (CoSEG). To detect co-saliency (segmentation) accurately, the core problem is to well model inter-image relations between an image group. Some methods design sophisticated modules, such as recurrent neural network (RNN), to address this problem. However, order-sensitive problem is the major drawback of RNN, which heavily affects the stability of proposed CoSOD (CoSEG) model. In this paper, inspired by RNN-based model, we first propose a multi-path stable recurrent unit (MSRU), containing dummy orders mechanisms (DOM) and recurrent unit (RU). Our proposed MSRU not only helps CoSOD (CoSEG) model captures robust inter-image relations, but also reduces order-sensitivity, resulting in a more stable inference and training process. { Moreover, we design a cross-order contrastive loss (COCL) that can further address order-sensitive problem by pulling close the feature embedding generated from different input orders.} We validate our model on five widely used CoSOD datasets (CoCA, CoSOD3k, Cosal2015, iCoseg and MSRC), and three widely used datasets (Internet, iCoseg and PASCAL-VOC) for object co-segmentation, the performance demonstrates the superiority of the proposed approach as compared to the state-of-the-art (SOTA) methods

The Role of Lumbar Sympathetic Nerves in Regulation of Blood Flow to Skeletal Muscle during Anaphylactic Hypotension in Anesthetized Rats.

During hypovolemic shock, skeletal muscle blood flow could be redistributed to vital organs via vasoconstriction in part evoked by activation of the innervating sympathetic nerve activity. However, it is not well known whether this mechanism operates during anaphylactic shock. We determined the femoral artery blood flow (FBF) and lumbar sympathetic nerve activity (LSNA) mainly regulating the hindquater muscle blood flow during anaphylactic hypotension in anesthetized rats. Anesthetized Sprague-Dawley rats were randomly allocated to the following groups (n = 7/group): (1) non-sensitized, (2) anaphylaxis, (3) anaphylaxis-lumbar sympathectomy (LS) and (4) anaphylaxis-sinoaortic denervation (SAD) groups. Anaphylaxis was induced by an intravenous injection of the ovalbumin antigen to the sensitized rats. The systemic arterial pressure (SAP), heart rate (HR), central venous pressure (CVP), FBF and LSNA were continuously measured. In the anaphylaxis group, LSNA and HR increased, while SAP and FBF decreased after antigen injection. In the anaphylaxis-SAD group, LSNA did not significantly change during the early phase, but the responses of SAP and FBF were similar to those in the anaphylaxis group. In the anaphylaxis-LS group, both FBF and SAP decreased similarly to the anaphylaxis group during anaphylactic hypotension. These results indicated that LSNA increased via baroreceptor reflex, but this sympathoexcitation or LS did not affect antigen-induced decreases in FBF or SAP. Lumbar sympathetic nerves are not involved in regulation of the blood flow to the hindlimb or systemic blood pressure during anaphylactic hypotension in anesthetized rats

Summary of the LSNA, FBF and FVR changes during anaphylaxis.

<p>The time-course data of LSNA (A), FBF (B) and FVR (C) after an intravenous injection of the ovalbumin antigen were shown. ● non-sensitized group; ○ anaphylaxis group; ◇ anaphylaxis-LS group; △ anaphylaxis-SAD group. n = 7 rats per group in this experiment. Values are expressed as means±SE. #P<0.05 vs. the non-sensitized group. *P<0.05 vs. the anaphylaxis group. The black, white and gray bars show the significant differences from the corresponding baseline values in the anaphylaxis group, anaphylaxis-LS group and anaphylaxis-SAD group, respectively.</p